1. Product Name:Metformin Hydrochloride Tablets
2. Product Description:
Metformin hydrochloride tablets








Indications?


Treatment of type 2 diabetes mellitus ,particularly in overweight patients, when dietary management and exercise alone does not result in adequate glycaemic control.


? In adults,metformin 850mg tablets may be used as monotherapy or in combination with other oral anti-diabetic agents, or with insulin.


? In children from 10 years of age and adolescents, Metformin tablets may be used as monotherapy or in combination with insulin.


A reduction of diabetic complications has been shown in overweight type 2 diabetic patients treated with metformin as first-line therapy after diet failure


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Posology and method of administration


Adults:


Monotherapy and combination with other oral antidiabetic agents:


? The usual starting dose is one tablet 2 or 3 times daily given during or after meals. After 10 to 15 days the dose should be adjusted on the basis of blood glucose measurements. A slow increase of dose may improve gastrointestinal tolerability.


The maximum recommended dose of metformin is 3g daily, taken as 3 divided doses.


? If transfer from another oral anti-diabetic is intended, discontinue the other agent and initiate metformin at the dose indicated above.


Combination with insulin:


Metformin and insulin may be used in combination therapy to achieve better blood glucose control. Metformin is given at the usual starting dose of one tablet 2-3 times daily, while insulin dosage is adjusted on the basis of blood glucose measurements.


Elderly: Due to potential for decreased renal function in elderly subjects, the metformin dosage should be adjusted based on renal function. Regular assessment of renal function is necessary?


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Children and adolescents:


Monotherapy and combination with insulin


? Metformin tablets can be used in children from 10 years of age and adolescents.


? The usual starting dose is one tablet of 500 mg or 850 mg once daily, given during meals or after meals.


After 10 to 15 days the should be adjusted on the basis of blood glucose measurements. A slow increase of dose may improve gastrointestinal tolerability. The maximum recommended dose of metformin is 2 g daily, taken as 2 or 3 divided doses.


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Contraindications


? Hypersensitivity to metformin hydrochloride or to any of the excipients.


? Diabetic ketoacidosis, diabetic pre-coma


? Renal failure or renal dysfunction (creatinine clearance erwards, and only after renal function has been re-evaluated and found to be normal?


Surgery:


Metformin Hydrochloride should be discontinued 48 hours before elective surgery under general, spinal or peridural anaesthesia. Therapy may be restarted no earlier than 48 hours following surgery or resumption of oral nutrition and only if normal renal function has been established.


Children and adolescents:


The diagnosis of type 2 diabetes mellitus should be confirmed before treatment with metformin is initiated.


No effect of metformin on growth and puberty has been detected during controlled clinical studies of one-year duration but no long-term on these specific points are available.


Therefore, a careful follow-up of the effect of metformin on these parameters in metformin-treated children, especially pre-pubescent children, is recommended


Children aged between 10 to 12 years:


Only 15 subjects aged between 10 and 12 years were included in the controlled clinical studies conducted in children and adolescents. Although metformin efficacy and safety in children below 12 did not differ from efficacy and safety in older children, particular caution is recommended when prescribing to children aged between 10 and 12 years.


Other precautions:


? All patients should continue their diet with a regular distribution of carbohydrate intake during the day. Overweight patients should continue their energy-restricted diet.


? The usual laboratory tests for diabetes monitoring should be performed regularly.


? Metformin alone never causes hypoglycaemia, although caution is advised when it is used in combination with insulin and sulfonylureas.





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3. Price:10.00
4. Product Website: http://www.sundentpharm.com/cardiovascul ar/metformin-hydrochloride-tablets.html< br />5. Company Description: Sundent Pharm Group
6. Address: ShanghaiShanghaiShanghaiSongjiangNo.1333 Xinlong Road, Shanghai.China.
7. Descption: Sundent Pharm Group (together with its subsidiaries, the Group”) is one of the largest comprehensive manufacturing, marketing, promotion and channel management service provider dedicated to pharmaceutical products.? Since establishment in 2004, the Group has determined to apply global vision to local management, and has introduced a series of pharmaceutical products embedded with technologies that represent international advanced level to China, South America, Eastern European and south Asia countries.? As of Dec 2015, the company had portfolio of pharmaceutical products, covering pain management, cardiovascular, respiratory, gastroenterology, immunology and other therapeutic areas.? At the same time, the Group endeavors to uplift the market value of these brands.

With a global horizon and well-deserved creditability in international market development, the Group has established long-term and stable cooperation with a number of renowned Chinese pharmaceutical manufacturer leaders, independent product quality analysis and develop centers, Chinese SFDA etc., The network lays the foundation of the sustainable development of the company through the comprehensive and effective products introduction and cooperation.

Looking into the future, the Group is committed to build itself into a cutting-edge pharmaceutical manufacturing and marketing group company that grasps the sales channel and product pricing advantage in mainland China. We believe that, with rapid development of China's pharmaceutical industry, through an open-minded attitude, perspective new product introduction capability, accurate product marketing strategy, comprehensive marketing network and effective management system, Sundent Pharmaceutical Group is able to achieve our development target.
8. Registered Capital: 50
9. EmployeeNum: 50
Sundent Pharm Group
10. Contact: Tracy zhang
11. Telphone: 86-21-67897115
12. Fax: 86-21-67897115
13. Email: Sundent@aliyun.com
14. Company Website: http://www.sundentpharm.com